Title

EVALUATION OF MACULAR PERFUSION AND FUNCTION THROUGH OCT-ANGIOGRAPHY BEFORE AND AFTER ENERGY DRINK INTAKE

Introduction

Energy drink consumption has been associated with cardiac arrest, myocardial infarction, spontaneous coronary dissection, and coronary vasospasm. This association is strengthened with studies showing increased platelet aggregation and increased systolic blood pressure. Our study aims to compare retinal perfusion using OCT-Angiography pre and post Energy Drink intake in healty patients.

Methods

Voluntary patients, between 21 and 40 years of age, without comorbidities and without contraindications for the intake of energy drinks and/or any of its main components. After reading and signing the informed consent form, patients underwent an OCT-Angiography exam scanned using the Angioscan OCTA software for the RS-3000 Advance OCT system (Nidek ). 40 eyes of 20 patients were evaluated 5 minutes before and 45 minutes after ingesting 500ml of energy drink containing 160mg of caffeine and 200mg of taurine. Vessel density, lacunarity and length were assessed using Angiotool Software® The following parameters were also evaluated (pre and post intake): best corrected visual acuity, sensitivity to contrast and color vision. The results before and after the energy drink intake were compared and send to statistical analysis.

Results

Only 02 eyes, of the same patient, did not show a statistically significant difference before and after the injection. 38 eyes of 19 patients showed a decrease between 47% and 52% in the macular, perfusion estimated by the Angio Tool indexes in the superficial plexus. However, functional changes have not been demonstrated (visual acuity, color vision and contrast sensitivity have not changed).

Discussion

This pioneering study demonstrated that there is a significant decrease in macular perfusion after 45 minutes of ingestion. However, randomized clinical trials with a larger number of patients are needed until we be able to indicate that a long-term chronic intake of energy drinks may compromise the retinal function secondary to macular perfusion decrease.

Keywords

retina; macula; optical coherence tomography angiography; energy drinks, caffeine; macular perfusion

Area

CLINICAL CASE

Authors

NELSON CHAMMA CAPELANES, CRISTIANE MOUTINHO, NATALIA CARVALHO, THAIANE FREITAS, Bernardo Kaplan Moscovi, CAIO SAITO REGATIERI