Title

CASE REPORT DENGUE VIRAL ACUTE DIFFUSE MACULOPATHY

Introduction

Dengue´s ocular manifestations are uncommon, but relevant.Data on dengue ocular involvement are still scarce in the literature, and references with longer follow-ups become even more uncommon.

Methods

The purpose of this abstract is to report a clinical case of dengue maculopathy after 3 years of clinical evolution.

Results

Male, 31 years, from Santos - SP, complains of sudden central vision loss of both eyes (OU) 3 years ago. Denies pain, trauma or any other ocular symptoms at the onset, but relates important fever and prostration at the occasion, had clinical diagnosis of Dengue fever, by the time. Now, maintains bilateral central scotomas, stable since then. Denies comorbidities and family history of ocular or systemic diseases. Best corrected visual acuity: Right eye (RE): 20/40 / Left eye (LE): 20/60 Biomicroscopy (OU): no alterations Fundoscopy (OU): preserved optic disk and vessels, rarefaction of retinal pigment epithelium (RPE) in circumscribed macular region. Visual Field Test (OU): Heighten indexes, bilateral fair central scotoma. Angiofluoresceinography (OU): diffuse fluorescence alteration at RPE, flocculated aspect.Alterations involve avascular fovea area, homogeneous and bilateral. Macular Optical Coherence Tomography (OCT): thinning and enlargement of foveal depression. Multiple micro-precipitates at external retina, beneath photoreceptor layer. Preserved Pachycoroid at both eyes. Electroretinography conclusion: cones and bipolar cells are preserved; ganglion cell layer is the loss focus;

Discussion

With this findings, retina dystrophic diseases were excluded; Neurodegenerative and infectious diseases were investigated through brain image and serologies. Case closed as sequel of viral Acute diffuse maculopathy, based on clinical history, serologies (dengue IgM neg/ IgG positive) and bibliography, Dengue etiology was the main hipotesis. We found scarce information about long-term follow-ups to compare, bringing the need to promote studies around dengue eye disease and its sequels.

Keywords

dengue; maculopathy; retina; virus maculopathy

File

Area

CLINICAL CASE

Authors

Ana Carolina Itano Horita, Ana CAROLINA Fernandes, Celso Afonso Gonçalves, Samuel Brunini Petrarolha

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