Title

ACUTE POSTERIOR MULTIFOCAL PLACOID PIGMENT EPITHELIOPATHY (APMPPE): CASE REPORT

Introduction

The APMPPE is a syndrome characterized by the appearance of multiple creamy-white plaque-shaped lesions located on the RPE. This entity generally affects young men and women, previously healthy, between the second and third decades of life. In most cases, the disease is bilateral and can affect the second eye in a few days. Patients experience rapid visual loss and may be accompanied by symptoms such as metamorphopsia, photopsy and paracentral scotomas

Methods

case report and literature review

Results

D. A. S., male, caucasian, 22 years old, born and living in Campinas - SP, seeks eye care for complaints of visual haze in both eyes for 3 days. Reports a history of flu-like symptoms for 7 days. Previously healthy. No ophtalmological or family history of note. At the initial examination, he presented visual acuity in Right Eye (OD) 20/40q and Left Eye (OS) 20/60q (whitout correction) . The biomicroscopy of both eyes was normal. Fundoscopy of both eyes presented a pinkish optic disc of normal dimensions, unaltered vessels, change in macular brightness with yellowish-white spots at the posterior pole, without vitreitis and applied retina. Angiography, retinography, and macula OCT were requested, as well as laboratory tests and sorologies. Based on these informations, some diagnostic hypotheses were suggested, such as MEWDS, Arbovirus and Pigmental Placoid Multifocal Acute Posterior Epitheliopathy (APMPPE).

Discussion

The visual prognosis of patients affected by APMPPE is usually good, but changes such as scotomas and permanent low vision may occur. It is important the accurate diagnosis of this pathology by means of imaging and laboratory tests, in order to differentiate it from another diseases that present themselves in a similar way initially, thus not delaying its treatment and monitoring.

Keywords

epitheliopathy and APMPPE and coroiditis

Area

CLINICAL CASE

Authors

Vinicius Clementino Falcão, Luis Felipe Ogliari, Valdez Melo Anjos Filho, Tiago Almeida Carvalho, Thiago Carvalho Silva Figueiredo, Bruno Badissera Tochetto, Fernanda Barbosa Nonato Federici, Marcio Augusto Nogueira Costa